PHENOTYPIC AND FUNCTIONAL CHARACTERIZATION OF THE CD6-ALCAM T-CELL CO-STIMULATORY PATHWAY AFTER ALLOGENEIC CELL TRANSPLANTATION

Phenotypic and functional characterization of the CD6-ALCAM T-cell co-stimulatory pathway after allogeneic cell transplantation

CD6 is a co-stimulatory receptor expressed on T cells that binds activated leukocyte cell adhesion molecule (ALCAM), expressed on antigen presenting cells, epithelial and endothelial tissues.The CD6-ALCAM pathway plays an integral role in modulating T-cell Outdoor activation, proliferation, and trafficking.In this study we examined expression of CD

read more


HBcrAg-based risk score performs better than the HBV DNA-based scores for HCC prediction in grey zone patients who are HBeAg-negative

Background & Aims: Risk scores have been designed to predict the development of hepatocellular carcinoma (HCC) in treatment-naive patients Food Storage Boxes with chronic hepatitis B (CHB).However, little is known about their predictive accuracy in HBeAg-negative patients in the grey zone (GZ).We aimed to develop a HBcrAg-based HCC risk score a

read more